endobj endobj 0000153649 00000 n EMC endobj endobj ET BT 72.000000 421.000000 Td BT endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000189935 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC Thats a prospective study on soft drinks and obesity. ) We like it in our bread, we like it in our pretzels, we like it everywhere we ) Tj 0000049583 00000 n If you did that everyday for a year, ) Tj 487 0 obj<> 72.000000 307.000000 Td stream EMC endstream BT stream EMC stream EMC endobj endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000188973 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj 72.000000 196.000000 Td 72.000000 687.000000 Td (die from lack of energy; they got energy. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream 560 0 obj<> endstream BT EMC 702 0 obj<> ET (fructose. (think so. ET 398 0 obj<> endstream 72.000000 508.000000 Td BT 0000161655 00000 n And he was worried that this was ) Tj (I show this is not just to show that the obese or getting obese, or of course that's true,) Tj How about the FDA? /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000106958 00000 n endobj Ancel Keys was ) Tj EMC BT 0000217075 00000 n 635 0 obj<> (rate of carbohydrate absorption in your gut, the bacteria get to it. 547 0 obj<> BT Arent we? ) endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj How many of you here have taken biochemistry? /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj (significant rise as the number of drinks went up. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj 0000061246 00000 n ET endstream EMC Well, you know what, if youre eating 187 or 335 calories more today than you were 20 years ago, your leptin aint working, because if it were, you wouldnt be doing it whether the food was there or not. endstream endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 128 0 obj<> 827 0 obj<> stream ET 0000026189 00000 n stream 0000010295 00000 n (it. This is a study done by our pediatric renal fellow Stephanie Winn just ) Tj 72.000000 227.000000 Td ET (going to tyrosine phosphorylated and this would be tyrosine IRS-1 which is now active. ) endobj EMC 144 0 obj<> Sugar disrupts leptin and ghrelin, two hormones that signal satiety in the brain, thereby lowering your hunger, and in effect, makes you eat more unneeded calories. Tj Tj 0000165025 00000 n (were never exposed to before 1975. EMC EMC 72.000000 386.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw The real ) Tj endstream 359 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (So here is lab fructose over here, crystalline fructose, and they are starting to put ) Tj (Why are the Koreans? 568 0 obj<> BT (because glycogen is easy to fish the glucose out with glucagon and epinephrine. stream (membered ring. endstream 72.000000 585.000000 Td endstream stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (called leptin. ET 72.000000 340.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endobj Well here is why, because it stimulates this guy over here called PP2A which ) Tj stream BT There were people lined up on both sides of the story. Eat your carbohydrate with fiber. endstream 72.000000 663.000000 Td (read a true prophecy you find this book, its not easy to find but if you go find this ) Tj 72.000000 530.000000 Td 0000047111 00000 n Tj BT endobj stream 0000111335 00000 n It's not about the ) Tj 0000122937 00000 n 81 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT stream American adult females are eating 335 calories more per day. endstream ET stream EMC ET 691 0 obj<> (water, you get thirstier. 25% of the adolescents today consume at ) Tj 78 0 obj<> BT (And then finally in the late 1970s we learned that LDL correlated with cardiovascular ) Tj ET 0000099904 00000 n 800 0 obj<> endstream (will tell you why, here is why. Plus there's a new literature that shows the more sugar the ) Tj endstream endobj ET stream endstream 0000000109 00000 n (to bind to its receptor and its going to take this substrate over here called IRS-1 ) Tj Everything else they dont have. endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream endstream 767 0 obj<> 365 0 obj<> 72.000000 163.000000 Td 504 0 obj<> 374 0 obj<> BT ET EMC Percent ) Tj 0000219851 00000 n (fructose no transport fructose on the beta cell that makes insulin. EMC 72.000000 297.000000 Td (decided to do a full transcript on his about 90-minute YouTube video called "Sugar: The ) Tj 0000146131 00000 n 0000172412 00000 n Tj endstream They had to ) Tj endstream stream endstream endobj 789 0 obj<> 72.000000 308.000000 Td EMC endobj stream 0000091400 00000 n EMC BT endobj BT 72.000000 698.000000 Td stream stream stream (environment. 189 0 obj<> (So here is acute ethanol exposure. 880 0 obj<> endstream endobj BT (That's exactly right. endstream 72.000000 262.000000 Td No question. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream (phosphate cant get out of the liver. EMC EMC endstream BT 0000068419 00000 n (reaction - the thing that happens on your grill happens in your arteries for the same ) Tj EMC stream ET BT BT (hypertension through that uric acid pathway; de novo lipogensis, dyslipidemia, hepatic ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw The only way to get glucose six phosphate out of ) Tj ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj BT <> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 72.000000 408.000000 Td Transcript 11:06:56 MS. DIANE REHM Thanks for joining us. 72.000000 553.000000 Td BT 871 0 obj<> EMC stream ET 0000107667 00000 n 292 0 obj<> ET EMC (terms, the standard interpretation of this law is the following: If you eat it, you ) Tj ET 72.000000 664.000000 Td EMC stream ET 0000032633 00000 n ET 72.000000 665.000000 Td stream 0000023083 00000 n stream ET 0000123657 00000 n endobj ET 0000057924 00000 n 72.000000 309.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (So what's in soft drinks?) stream 72.000000 352.000000 Td 0000101577 00000 n Read An Excerpt This article has been adapted by arrangement with Hudson Street Press, a member of Penguin Group (USA) Inc., from "Fat Chance" by Robert Lustig M.D. 0000018233 00000 n ET EMC 0000169765 00000 n (way and high-fat diet gets in the way. stream 72.000000 632.000000 Td This story has a little bit of something for everybody. endobj ET So we have three times the substrate and there's the rub. endstream 529 0 obj<> 522 0 obj<> endobj ET 736 0 obj<> EMC BT ET BT BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (at Saga Medical School in Japan by a guy named Takasaki who is still alive. Tj We talked about this before, Gatorade AM. BT 72.000000 121.000000 Td BT endobj Tj (lipogenesis. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET endobj 0000031183 00000 n So they are talking about soda like ) Tj 0000145426 00000 n 415 0 obj<> stream 0000056976 00000 n endobj BT stream Partial correlation analyses show ) Tj 72.000000 262.000000 Td 0000174505 00000 n BT EMC stream ET You know Rossini, the famous composer, he retired at age 37 to a lifetime of gastronomic debauchery. ET Number two, it's your endogenous stress ) Tj 72.000000 308.000000 Td ET endstream Now in order to talk about the environment we need to talk about what is obesity, and of course, youre all familiar with the basic concept of the first law of thermodynamics, which states that the total energy inside a closed system remains constant. sugar-the-bitter-truth-transcript-pdf 1/2 Downloaded from thesource2.metro.net on April 22, 2023 by guest Sugar The Bitter Truth Transcript Pdf Yeah, reviewing a book sugar the bitter truth transcript pdf could ensue your near connections listings. endstream (governing food additives, it is required the additives be safe, defined as reasonable ) Tj stream EMC 0000054312 00000 n endobj And there is a huge literature that's now ) Tj (So how about type 2 diabetes? EMC EMC (way into everything. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 540 0 obj<> EMC 0000046385 00000 n 72.000000 132.000000 Td ET (regulations explicitly postulate a connection between such products and such diseases. endstream (steatosis through that DNL pathway, those three enzymes, the new fat making pathway; ) Tj 72.000000 272.000000 Td 616 0 obj<> 72.000000 151.000000 Td EMC stream stream 72.000000 362.000000 Td endobj BT endstream stream endobj Tj (So theres something wrong with our biochemical negative feedback system that normally ) Tj endobj 764 0 obj<> 421 0 obj<> They both eliminate the sugar fructose. ) 901 0 obj<> stream 393 0 obj<> endobj 72.000000 508.000000 Td 205 0 obj<> EMC 482 0 obj<> 72.000000 597.000000 Td endstream EMC endobj BT But there is a lot about how sugar operates that we may not have realized before. stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 448 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 72.000000 420.000000 Td 72.000000 432.000000 Td (active. Now does fructose meet that standard? Computers? stream endstream EMC 0000086957 00000 n endobj 317 0 obj<> 0000147338 00000 n EMC stream 661 0 obj<> BT 0000071987 00000 n endobj BT BT endstream (course, youre all familiar with the basic concept of the first law of thermodynamics, ) Tj stream stream stream 72.000000 609.000000 Td ET stream EMC endobj 0000174267 00000 n (Were also fatoholics. EMC 72.000000 363.000000 Td BT endobj endobj (that that's the worst thing you could do and thats what weve done, and were still ) Tj (axis and so you would say look at that, its very obvious, isnt it? 296 0 obj<> >>/Contents [ 238 0 R 239 0 R 240 0 R 241 0 R 242 0 R 243 0 R 244 0 R 245 0 R 246 0 R 247 0 R 248 0 R 249 0 R 250 0 R 251 0 R 252 0 R 253 0 R 254 0 R 255 0 R 256 0 R 257 0 R 258 0 R 259 0 R 260 0 R 261 0 R 262 0 R 263 0 R 264 0 R 265 0 R 266 0 R 267 0 R 268 0 R 269 0 R 270 0 R 271 0 R 272 0 R 273 0 R 274 0 R 275 0 R 276 0 R 277 0 R 278 0 R 279 0 R 280 0 R 281 0 R 282 0 R 283 0 R 284 0 R 285 0 R 286 0 R 287 0 R 288 0 R 289 0 R 290 0 R 291 0 R 292 0 R 293 0 R 294 0 R 295 0 R ] >> endobj (it, right? /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET (problems which we'll talk about in a moment. The fact that the incidence ) Tj And I would very much appreciate if at the end of the talk you ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 905 0 obj<> endstream 158 0 obj<> stream 72.000000 363.000000 Td If you have impending heart and diabetes problems then pay attention to what this man has to say.. (transitive, but in fact, only the contrapositive is transitive. endstream In other words, donuts, and wherever there was the fat, there was ) Tj 0000185856 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 164.000000 Td 82 0 obj<> So a small increase from the beginning of the century to World War II. (With that, think about what it means to be on a diet and what macro-nutrients you are ) Tj 30 0 obj<> endstream endobj
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